WebMar 22, 2024 · Crystal-Forming Drug Nephrotoxicity. Sulfa drugs, acyclovir, methotrexate, ethylene glycol, and protease inhibitors such as indinavir cause acute kidney injury (AKI) by tubular obstruction due to crystal formation in the tubular urine. Webwww.karger.com
Nephrotoxicity of anticancer treatment Nephrology Dialysis ...
WebDrug-induced nephrotoxicity is increasingly recognized as a significant contributor to kidney disease including acute kidney injury (AKI) and chronic kidney disease … WebTecovirimat has been used in a 28-month-old child with no adverse eects attributed to the drug, but no clinical studies have. been done in pediatric populations. Monitoring of renal function is recommended in pediatric patients < 2 years of age, given ... Animal studies have shown potential for nephrotoxicity at very high exposure levels of ... emily schied
Nephrotoxicity - Wikipedia
WebApr 3, 2024 · Drug-induced nephrotoxicity is increasingly recognized as a significant contributor to kidney disease including acute kidney injury (AKI) and chronic kidney disease (CKD). Nephrotoxicity has a wide spectrum, reflecting damage to different nephron segments based upon individual drug mechanisms. Both glomerular and tubular injuries … WebJun 6, 2024 · Acute kidney injury (AKI) is a global health challenge of vast proportions, as approx. 13.3% of people worldwide are affected annually. The pathophysiology of AKI is very complex, but its main causes are sepsis, ischemia, and nephrotoxicity. Nephrotoxicity is mainly associated with the use of drugs. Drug-induced AKI accounts … WebOct 6, 2016 · Abstract. Severe adverse systemic drug events occur commonly as a result of treatment of cancer patients. Nephrotoxicity of chemotherapeutic agents remains a significant complication limiting the efficacy of the treatment. A variety of renal disease and electrolyte disorders can result from the drugs that are used to treat malignant disease. emily schick